Brain-Tools

Molecular basis for high specificity of MSF for brain, and lack of toxicity in peripheral tissues.

Effects of a Central Anticholinesterase, Methanesulfonyl Fluoride on the Cerebral Cholinergic System and Behavior in Mice: Comparison with Organophosphate DDVP (1999)

Another comparative study looking at MSF versus DDVP in regards to their ability to permanently turn off an enzyme that dismantles the Acetylcholine needed to form memories. The study showed that while more effective in the short term, DDVP wore off sooner than MSF and induced secondary effects that suggested toxicity with a single injection. MSF, again, produced no observed toxic side effects except after repeated injections, while outlasting the DDVP in the long term.

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